With garlic, turmeric& co. Against the coronavirus?

Coronaviruses on cell

Is against viruses actually a herb grown? The biochemical simulation that "suggesting the conclusion", that 17 components of the Garlic’s "are a valuable, natural antiviral source that helps prevent the invasion of the coronavirus into the human body.", published on 2. April 2020 a team of researchers from various universities in Vietnam (1). Which plants can we use to prevent or fight viral infections?? Does it really work? Back in 2010, the World Health Organization (WHO) called for research into this. What results did the researchers’ evaluations, equipment and electron microscopes reveal?

(Photo: Coronaviruses (yellow) on an infected cell. Courtesy: National Institute of Allergy and Infectious Diseases, US. Licensed under a Creative Commons License 2.0)

The WHO’s suspicion was very well founded that Ayurvedic medicine, traditional Chinese medicine and other naturopathic teachings, which have proven to be very effective, know herbal defense weapons against viruses. The first positive research results were on the table. And for a long time naturopathy has contributed in many cases to the prevention and cure of pneumonia, influenza and other viral diseases. Only, the healers and doctors of the past didn’t know that viruses and bacteria affected the sick. They only saw the signs of illness: Fever, cough, cold, diarrhea, shortness of breath, … .

The discovery of viruses

That viruses often do the destructive work was first brought to light by electron microscopes since their invention in 1931. Two-million-fold magnification revealed viral invasion. But people could also now accurately track the body’s defense army of phagocytes, killer cells and other defensive weapons with their eyes. Killer cells became recognizable, destroying the cells of our body where viruses have invaded to multiply. Because the insidious viruses enter our cells and reprogram them to produce the invaded virus.

This insidious mechanism is prevented by a spice, more precisely the yellow dye curcumin from turmeric (turmeric) in some tested virus species. In January 2018, a team of researchers from two universities in Taiwan published their research finding on the antiviral mode of action of curcumin (2). Curcumin prevents the cells of our body affected by the tested viruses from making the virus. Even in different pathways (see graphic). For one thing, curcumin prevents the virus from attaching itself to a cell and penetrating. And inside the cell, curcumin keeps the cell from replicating the virus. This stops the virus from multiplying – known as replication in technical terms.

Mode of action of curcumin

Curcumin& Co against coronavirus?

If the viral defense mechanisms of curcumin& Co also effective against the SARS-CoV-2 coronavirus? Researches, of universities dealing with traditional natural remedies, are in full swing to provide biochemical and clinical evidence for it. An am 8. April 2020 computer simulation published by Utkal University in India (3) said "the possibility" predicted that curcumin from turmeric and catechin, which makes up 30-40% of green tea, for example, are effective against the currently spreading coronavirus. Catechins are also found in many fruits – such as apples, apricots, pears, blackberries, strawberries, raspberries, black currants, peaches, plums, quinces, sour cherries, gooseberries, sweet cherries, and grapes (4).

Garlic in use against viruses

Garlic was also tested. The evidence provided by a team of researchers from various Vietnamese universities using the molecular docking technique suggests, according to the study, that 17 components of garlic fight the coronavirus in the same ways that curcumin has been shown to do for some types of viruses: preventing the coronavirus from entering our cells and being replicated by our cells. Essential garlic oil obtained by distillation of fresh garlic was studied (1).

A 2001 study shows the efficacy of garlic in the treatment of the common cold, probably the most common viral illness in the world. 146 participants were given either one capsule of a garlic supplement (containing 180 mg allicin) or one capsule of an ineffective placebo daily for 12 weeks. During the trial period, 24 cases of colds occurred in the group taking the garlic preparation and 65 cases of colds in the placebo group. When someone in the placebo group got a cold, it lasted an average of 5 days. In the garlic group, a cold lasted an average of 1.5 days. The results of this test show both the preventive and immune system-boosting effects of garlic (5).

This solidly conducted research on garlic in capsules has a certain flavor, as its author sells 30 capsules for $39.95 on his website. Studies cost money. That is why many of this kind are financed today by companies that produce food supplements. Most of the time, of course, the manufacturers’ studies deal with a component or extract of the plant, which is also effective as a whole plant. Studies by government agencies or foundations with only the welfare of people in mind could also show that a natural plant may do more than a single active ingredient extracted from the plant.

The possible tendency to doubt the effect of garlic due to study funding is countered most impressively by the study of Professor Kyu Hang Kyung Ph.D., Doctor of Nutritional Science at Sejong University in Seoul, the capital of South Korea, countering. It concludes in 2011: Wild garlic (Allium ursinum) and Garlic (Allium sativum), inhibit all microorganisms tested such as bacteria, fungi, viruses and parasites.

The university study also shows that it is not necessary to pack the bulbous plants in capsules. Garlic and wild garlic also act fresh. Prolonged heating volatilizes or changes some of the components that are effective against microorganisms. But when combined with oil, the main active ingredient that is effective against viruses, allicin, forms what are known as ajoenes, which were even more aggressive than allicin against the viruses studied in the test tube (6) (7).

Another study from Mexico demonstrates that garlic improves overall immune system function (8).

Consequently, to maintain immune-boosting potency, two options emerge: Onion spices best either chopped small mixed with the salad or stirred shortly before the end of the cooking process in the food wetted with fat – at least part of the small chopped. In pandemic times, this also helps people who are sensitive to odors to maintain the minimum distance of 1.50 m.

Ajoene can be produced by growing a Wild garlic– or Garlic oil Prepared. Just put olive oil, with salt, wild garlic or garlic in a blender and puree the whole thing finely. This makes sense especially with the green leaves of the bear’s leek, which only see the light of day for about 3 months. It is recommended to harvest the leaves before flowering, because then they taste best. Wild garlic oil in a sealed jar will last many months in the refrigerator.

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The defense strengthening vegetables and herbs

Even the ordinary Kitchen onion (9), the Shallot (10) and leeks help the body prevent certain viral infections, according to science. Leek (11) also proved to be the most effective vegetable in studies involving the coronavirus SARS-CoV, which was discovered in 2002.

The spices that give dishes that spicy, Italian taste – Rosemary (12, 13) and Thyme (14) – as well as Ginger (15) also contain active ingredients that have been proven in scientific research to support our immune system in the fight against the tested viruses.

Among the plants that are enjoyed as tea, there are those with outstanding antiviral properties. These include the Tulsi, also called Indian basil (Ocimum sanctum Linn), the Cistus rose (Cystus incanus) and the Licorice root (Glycyrrhiza glabra).

Tulsi strengthens the immune system

With Tulsi, also known as holy basil, Ayurvedic medicine has long been treating respiratory diseases. In November 2005, a study published in the journal Clinical and Experimental Pharmacology& Physiology an article by a Taiwanese research team that provided evidence that tulsi kept 5 types of viruses studied from infecting cells and stopped the viruses from multiplying in the cells (16). This so-called in vitro experiment, conducted in glass test dishes or test tubes, was followed half a decade later by a study with humans, a clinical trial.

In a double-blind clinical trial of tulsi conducted by the All India Institute of Medical Sciences in New Delhi, India in 2011, a group of 24 healthy adults were divided into two groups. One group received 300 mg of a tulsi basil extract daily on an empty stomach; the other received a placebo. None of those tested knew whether they were receiving the ineffective placebo or the Tulsi extract in the same looking capsule. After 4 weeks, blood was drawn from everyone again. It was found that in the group that received the tulsi extract, there was a significant increase in natural killer cells and T-helper cells in the blood. Both types of defense cells are involved in fighting viruses in the body. The fact that there was also an increase in interleukin IL-4 in the blood of those who belonged to the tulsi group is a measure in medicine that those tested had a stronger immune system after the ingestion period (17).

Black elderberries effective against influenza viruses

Since it is known that an infection with viruses can lead to a so-called superinfection – an infection of the lungs with bacteria – the Institute of Medical Microbiology at Justus Liebig University in Giessen, Germany, in 2011 investigated the effect of a liquid extract of the black elderberry (Sambucus nigra) for both influenza A and B viruses and 4 types of bacteria responsible for upper respiratory tract infections. Researchers showed that a liquid extract of black elderberry has antimicrobial activity against the bacteria studied. They also noted: "The liquid extract also showed an inhibitory effect on the replication of human pathogenic influenza viruses. (18)"
Back in 1995, a team of researchers from the Hebrew University of Jerusalem published a double-blind study on an elderberry extract. 90% of patients with "influenza B/Panama" infection who took an extract of elderberry, was completely healthy again after only 2 – 3 days. The patients who received a placebo needed at least 6 days to do so (29).

Another study showed that an extract of black elderberries activates a healthy immune system by producing more pro-inflammatory cytokines (20). For this reason, cautious herbalists recommend using black elderberry only as a preventative measure and at the beginning of an illness with flu symptoms. They advise against ingesting elderberry preparations when there is an advanced stage of infection, such as with the novel coronavirus. This is because infection with the SARS-CoV-2 coronavirus, when the infection reaches this stage, can result in an excessive increase in pro-inflammatory cytokines. This stage would likely be exacerbated by ingestion of black elderberry preparations (21).

Black elderberries should be consumed only when ripe, or as a syrup or extract, as there are some reports of poisoning with the fresh juice of elderberry species. The poisonings originate from sambunigrin, which is present in unripe elderberries. The toxic prussic acid can be released from it. It can cause nausea and vomiting. Hence the recommendation: Use only ripe fruits in cooking and boil them briefly. That makes them digestible. And don’t boil them too long, because that destroys the vitamin C they contain.

Blackcurrants

An extract from the black currant Prevented the multiplication of influenza A and B type viruses in a cell culture. After 6 to 9 hours of exposure to infected cells, the infection of the cells had completely disappeared. This was shown in a trial at Asahikawa Medical University in Japan in 2003 (22). In Tohoku Medical and Pharmaceutical University in Japan, experiments with other types of viruses were conducted in 2012. One finding: the extract prevented viruses from multiplying by more than 50% at a black currant concentration of less than 1% (23).

In mice infected with influenza viruses, administration of an extract from the leaves of the black currant bush resulted in a decrease in the number of viruses in the mice. This was proven by scientists from the University of Tubingen, Germany. The study states: "Furthermore, we have shown that the mechanism of action is based on the extract preventing uptake of the viruses into the host cell (24)." The Japanese and German researchers conclude: black currant and also the leaves of the bush are very effective against various strains of viruses that cause diseases of the respiratory tract.

Experiments with viruses in cell cultures transferable to humans?

Are experiments with viruses in cell cultures and with animals at all transferable to humans? Why researchers conduct experiments with cell cultures, and why the answer to this question is often yes, is shown by the History of the invention of penicillin. In September 1928, Scottish bacteriologist Alexander Fleming finds a shallow glass dish containing a moldy bacterial culture in his laboratory. He had just returned to his laboratory from summer vacation. The dish had been left unwashed in the sink. Before his departure, Fleming experimented with the bacterium Staphylococcus aureus. He sees: the green molds have destroyed the bacteria. It succeeds in extracting the bacteria-killing substance from the mold. Fleming noted: "Penicillin generally does not damage the body’s cells, but it kills a very large number of dangerous pathogens." Penicillin was born. But his hour came nearly two decades later, after other researchers picked up on Fleming’s findings and developed a process to produce penicillin (25).

Cistus rose test at the Charite University Hospital in Berlin

The Cistus rose (Cystus incanus) grows in the Mediterranean region and has long been used in the traditional medicine of southern Europe against flu-like infections, among other things, without any side effects being apparent. Evidence of the bush plant’s medicinal use dates back to the 4. Century before Christ back. Aware of the danger posed by influenza viruses, which kill thousands each year, in 2007 researchers at the Institute of Molecular Virology at Westfalische-Wilhelms-Universitat in Munster, Germany, studied a polyphenol-rich extract of cistus rose – called CYSTUS052 – on its effectiveness. They infected cell cultures with various influenza viruses and found that the extracted constituents of cistus rose effectively prevented the virus from entering the cells, resulting in significantly fewer offspring of the viruses. The influenza viruses were also unable to develop resistance to the cistus rose extract. Which means that CYSTUS052 also prevented the multiplication of the ever-changing offspring of the influenza virus (26). Vaccinations and drugs against the influenza virus are therefore often soon ineffective and only partially effective, because it continuously produces new forms of its kind.

In 2009 with the cistus rose a clinical study conducted at the Charite in Berlin, one of the largest university hospitals in Europe. Here, doctors and scientists research, heal and teach at a top international level. More than half of Germany’s Nobel Prize winners in medicine and physiology have come from the Charite, including Robert Koch. In the placebo-controlled study, a randomly selected portion of 160 patients with upper respiratory tract infection received CYSTUS052 rockrose extract. Many of the cold symptoms, as well as the inflammatory marker C-reactive protein, decreased to a significant degree in the cistrose group, while there was less marked improvement in the placebo group (27).

In 2013, a team of virologists and immunologists from the University of Munster and the University of Tubingen published the following regarding cistus rose extract and an extract from black currant leaves: "The main effect would rather be described in the physical sense as non-specific anti-adhesive. This is also consistent with its broad antiviral activity against a wide variety of viruses, and holds another advantage: pathogens cannot easily evade the relatively nonspecific attack by mutation, so that, for example, no resistant influenza pathogens were found after Cystus052 treatment. In summary, anti-adhesive plant products, in the sense of the WHO Call to Action, are a promising option for the antiviral treatment of respiratory viruses. Because of the low risk of side effects, not only therapy but also [prevention] prophylaxis should be considered here (28)."

Researched plants also effective against new COVID-19 virus?

The crucial question is: Do the researched plants also show effect in the prevention of the novel coronavirus infection or can they even support a healing of the disease?

Prof. Dr. Andreas Michalsen, holder of the endowed professorship for clinical naturopathy at the Unversitatsklink Charite in Berlin, answers the question as follows: "Sage, rosemary, thyme, bay leaves, licorice, wild garlic and garlic, also Turmeric, mustard oils, propolis and especially that in the Green tea contained epigallocatechin show antiviral effects. Now also for naturopathy the COVID-19 virus is new, d.h., it cannot be assessed that the antiviral effects shown in studies on SARS or MERS are also transferable to COVID-19. However, since these measures are safe and basically also strengthen the body, I am happy to recommend them (29)."

Among other things, Professor Michalsen also recommends Meditation to strengthen the immune system. Studies indicated that when we practice meditation, the antibody response after a vaccination is stronger and more effective. In addition Relaxation techniques such as meditation, yoga, tai chi and breathing exercises Alleviate fears and worries that weaken our immune defenses.

That The positive effects of meditation on our emotional life also improve the immune defense, showed Dr. Richard J. Davidson Ph.D. and Prof. Jon Kabat-Zinn, the two most outstanding representatives of contemplative neuroscience, already in 2003 in a study. In the blood of a group of meditators, after 8 weeks of regular practice, significantly more antibodies were found following a flu vaccination than in the blood of the control group. It turned out that the more comfortable the studied people feel through regular practice of meditation, the stronger is the activity of the left hemisphere of the brain and correspondingly higher is the number of immune cells in the blood (30).

Professor Michalsen likes to recommend naturopathic measures because "most naturopathic therapies are known to strengthen the body’s immune defenses. (29)" And only it manages at present surely to defeat COVID-19. That show the recovered and those who have the virus in a certain extent demonstrably in itself, but do not perceive any signs of illness at all. The whole Recommendations from Prof. Dr. Andreas Michalsen to the stabilization of the immune defense are to be found here ".

A free, simple and proven Instruction, to learn meditation, can be found here "

The ayurvedic home remedy kadha – an effective preventive measure?

A suggestion that spices and herbs may play a part in preventing and managing coronavirus infection came on 14. April 2020 from the Bhabha Atomic Research Centre in Mumbai (formerly Bombay), India. An investigation using "molecular docking" computer simulation showed that Ashwagandha, black pepper, cardamom, cloves, garlic, ginger, guduchi, tulsi, the lemon and turmeric (turmeric), contain active substances that prevent the coronavirus from entering the cell in the generated computer graphic. The above products of the plant world are used as part of Ayurvedic preparation Kadha Used mainly in India as a home remedy for the prevention and treatment of respiratory diseases such as coughs, colds and flu.
The research group writes: "Our study has identified a number of plant compounds in these herbs that show significant docking hits and the potential to block different stages of SARS-CoV-2 infection as well as different coronavirus targets. This preparation can strengthen individual immune defenses and prevent the severe course of viral disease by interfering with various stages of viral replication in the infected individual. (31)"

A somewhat bold choice of words based on a computer simulation. Whether it proves true, Ayurveda doctors will see in individual cases and in certain stages of an infection. As a rule, very experienced Ayurvedic doctors administer herbal mixtures, which they compose after examination specifically for a patient and his current condition. Such words can surely be chosen by a research team only in a country like India, where people have had many positive experiences with Ayurvedic medicine and especially with the home remedy Kadha. Ayurveda in India is not a wellness program for the wealthy, but an integral part of public health care. In almost all cities of India there is at least one governmental Ayurveda hospital, altogether about 2500. Ayurveda is a system of medicine recognized by the World Health Organization (WHO), and an effective one: prof. Dr. Andreas Michalsen writes in his bestseller "Healing with the Power of Nature" that the Ayurvedic doctors he works with in his environment are often still able to alleviate the complaints of patients for whom Western naturopathy could do nothing more.

And sometimes it is just a Mixture of herbs, which causes the more relief or cure. This shows a scientifically researched example. In India Turmeric as a rule together with ground black pepper and butter fat (ghee) or oil mixed into the food. Scientists found that the addition of pepper to turmeric causes up to 2000% more curcumin than if the food was seasoned with turmeric alone (32). The reason for this is that the substance piperine, which makes the pepper spicy, causes the curcumin not to bind to water in the liver and therefore cannot be excreted by it (33). Due to the Fat addition is found in studies again 7 to 8 times more curcumin in the blood, because the turmeric components mix with fat and are thus directly absorbed by the lymph. This bypasses the liver, which normally excretes many turmeric constituents (34).

The licorice root: use in China against COVID-19

In laboratory tests with the coronavirus, which caused respiratory illness in 2002 and subsequent years, had been found in the Luton& Dunstable Hospital NHS Foundation Trust in the UK found that the glycyrrhizin of the Licorice root the most effective antiviral ingredient was. Glycyrrhizin is the sweetening molecule of the root and tastes about 50 times sweeter than cane sugar. That is why only half a teaspoon of the granulated root makes a liter of tea taste sweet (35). In Ayurvedic teas, licorice root is often used as a sweetener but also as an effective medicinal ingredient. Another advantage: this sweetness does not produce caries.

And exactly the licorice root is an effective main ingredient of the "Qingfei Paidu" decoction, which is currently successfully used in China for the treatment of the currently spreading SARS-CoV-2 coronavirus. It contains a total of 21 different herbs, 16 of which are aimed at strengthening the lung meridian. Chinese medicine heals by strengthening certain energies in organ systems and meridians, which in turn activates the body’s self-healing powers. In the normal to severe cases treated with Qingfei Paidu, among other things, a 70% increase in lymphocytes was achieved in the immune system of the patients. Practical experience with the "Qingfei Paidu" decoction in clinics has led to it becoming part of the Ministry of Health’s official diagnosis and treatment plan against pneumonia caused by the new coronavirus in China. The published study shows that "Qingfei Paidu" accelerated the process of healing in 90% of patients (36).

But in several patients, other Chinese herbal mixtures have been more successful. Traditional Chinese medicine (TCM) is also effective, according to its proponents, because it can identify the energetic weaknesses of individual patients and administer herbal mixtures tailored to them.

Homeopathy too weak against viruses?

Homeopathic associations and physicians, for example, from India, who treat patients in many countries, report considerable success in treating the symptoms caused by the new coronavirus (37). Because of the visible success of Homeopathy even in the case of infections and the most severe diseases, which many Indian citizens had experienced, the Indian government recognized homeopathy as one of the national systems of medicine in 1973. She established the Central Council of Homeopathy to regulate continuing education and the practice of homeopathy. Since then, only qualified, registered homeopaths are allowed to perform homeopathic treatments in India. Currently there are over 200,000 homeopathic physicians in India with annual increase. (38) In India, many orthodox physicians, Ayurvedic physicians and homeopaths work together and send each other patients. They weigh up which treatment method promises the best healing success for the patient in each case. The Central Council for Research in Homeopathy in the Indian capital, New Delhi, has also launched a project to Research on the efficacy of homeopathy in epidemic diseases launched (39).

Reports of the Association of Homeopathic Physicians in China under the direction of Dr. According to Aron To, president of the Hong Kong Association of Homeopathy, homeopaths searched intensively for the remedy that corresponds to the most common typical symptoms in the current coronavirus infection. Over 30 homeopathic physicians in China found a main remedy by matching the symptoms of their patients. Two others crystallized. Which is the right medicine for an individual can usually only be determined by an experienced doctor. (40)

Physicians working with homeopathy point out that each patient must be considered individually. Due to of his particular disease symptoms and his individual innate constitution everyone needs a different homeopathic remedy that helps the disappearance of the signs of the disease. In the course of treatment, other homeopathic remedies may also be required to restore health. In the framework of the international medical congress "United to Heal" held online from 9.- 19. April 2020, it has been shown that there is not one genius epidemicus (one main remedy) in this pandemic, but up to 30 homeopathic medicines to combat the individual signs of the disease, depending on the stage of the disease and partly also depending on the country and the region. Participants at the medical congress report that they have successfully treated hundreds of coronavirus infections with these 30 remedies, including those with pre-existing conditions. (41)

Prevention with homeopathy

prevention with homeopathic remedies is also possible, even if they feel healthy or suffer from a chronic disease. To do this, the homeopath of her confidence must conduct an interview (anamnesis), by which he records the sum of all her innate physical and mental characteristics (constitution), as well as previous illnesses and present signs of illness (symptoms). Based on this questioning, the homeopath is able to find the right homeopathic medicine for you.

Homeopathy and epidemics

In his webinar " from 4. April 2020 showed Dr. Andre Saine N.D. from the American Institute of Homeopathy, a homeopathy teacher who is in great demand in Canada, the USA and Europe, showed in a comparison that during the Spanish flu of 1918, the mortality rate of patients treated with homeopathy who had pneumonia was 8 times lower than the mortality rate of patients with pneumonia treated only conventionally at that time. (42) Impressive is also a document " by Dr. Anton Rohrer from Austria, which compiles the successes of homeopathy in earlier epidemics from historical documents. Dr. Rohrer has been a lecturer in homeopathy at the Medical University in Graz, Austria, since 1996. (43)

In conclusion, experiment with home remedies when you are infected, can delay the healing process and thus make the infection worse. This is not advisable in the case of an infection that can leave permanent damage or in the worst case even lead to death. In the event of an infection, for their own good, contact an experienced doctor they trust immediately, who will be able to provide treatment tailored specifically to them and the stage of their infection. And last but not least: Prevention is better than cure. The prevention is helped by the sensible advice of the health ministries and those proven measures they choose to strengthen their immune system.

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